Gastroesophageal reflux disease (GERD) occurs commonly in Western countries.
Clinical trails involving GERD patients rely heavily on the patient's self-assessment using questionnaires.
In this study, researchers evaluated the validity of the currently available GERD measurement tools.
|The team identified 5 scales which met some, but not all of their criteria.|
|Alimentary Pharmacology and Therapeutics|
They established that an ideal GERD symptom assessment questionnaire, suitable for use in clinical trials, should fulfill a number of criteria:
- Be sensitive in patients with GERD.
- Cover the frequency and intensity of typical and atypical GERD symptoms.
- Be multidimensional.
- Have proven psychometric properties (validity, reliability and responsiveness).
- Be practical and economical.
- Be self-assessed.
- Use "word pictures" which are easy to understand for patients.
- Respond rapidly to changes (responsiveness over short time intervals).
- Be used daily to assess changes during and after therapy.
- Be valid in different languages for international use.
The team performed a search of the literature.
They identified 5 scales which met some, but not all of the criteria.
Dr Stanghellini's team concluded, "There is a need for a new evaluative tool for the assessment of GERD symptoms and their response to therapy".