Curative treatment of Helicobacter pylori infection reduces the relapse of peptic ulcers.
In this study, physicians from Japan evaluated the recurrence rate and specific features of peptic ulcers after H. pylori eradication.
|Peptic ulcer recurrence rate was 3.2%.|
The team assessed 4940 peptic ulcer patients who were H. pylori negative after successful eradication treatment. They followed these patients for up to 48 months.
The physicians recorded the annual incidence of ulcer relapse, the background of patients with relapsed ulcers, time to relapse, ulcer size, and site of relapsed ulcers.
The team calculated the peptic ulcer recurrence rate to be 3.2%.
The annual recurrence rates of gastric, duodenal and gastroduodenal ulcers were 2.3%, 1.6%, and 1.6%, respectively.
When the physicians excluded patients who took NSAIDs the annual recurrence rates were 1.9%, 1.5% and 1.3%, respectively.
They determined that the recurrence rate was significantly higher for gastric ulcers.
In addition, the team found that gastric ulcer recurrence rates in patients who smoked, drank alcohol, or used NSAIDs were significantly higher, compared to duodenal ulcer recurrence.
Dr Hiroto Miwa's team concluded, "Curative treatment of H. pylori infection is useful in preventing ulcer recurrence."
"Gastric ulcer is more likely to relapse than duodenal ulcer."
"Recurrent ulcer tended to recur at the site of the original ulcers."