The research at the University of Leicester, England, involved 15 patients with advanced cancer.
P54 comes from the spice turmeric
They took daily doses of P54 for four months. P54 comes from the spice turmeric, and was developed by Phytopharm plc, of Godmanchester, Cambridgeshire, England.
Researchers said there was a dose-dependent decrease in COX-2 levels. In three patients the disease stabilized for 3 months, and in two patients it stayed stable for 4 months.
Researcher Professor Will Steward said, "We are all cautiously optimistic that inhibition of COX-2 may be an important mechanism to reduce cancer risk.
"The results of this trial appear to confirm that P54 is able to inhibit COX-2 and may have a role in the prevention of colon cancer, and, possibly, could form part of a treatment regimen for established disease."
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