Active upper-GI bleeding or a visible vessel at endoscopy are considered high-risk lesions predicting bleeding recurrence.
In this study, investigators from Calgary, Canada, determined whether nasogastric aspirate can predict the presence of high-risk lesions.
The team identified 520 patients with upper GI bleeding who underwent nasogastric aspiration and subsequent endoscopy.
|Bloody nasogastric aspirate was significantly associated with high-risk lesions.|
The investigators found that a bloody nasogastric aspirate was significantly associated with high-risk lesions (odds ratio 4.82).
This also had that highest specificity for high-risk lesions (76%), with a negative predictive value of 78%.
Bloody nasogastric aspirate raised the probability of having a high-risk lesions from 0.29 to 0.45, while clear nasogastric aspirate reduced the likelihood to 0.15.
The team determined that nasogastric aspirate yielded the most information in hemodynamically stable patients without hematemesis.
Dr Abdulrahman Aljebreen's team concluded, "Nasogastric aspirate is useful in predicting high-risk lesions".
"Whether it can be used to determine which patients would benefit from earlier endoscopy deserves further study".