In this study, doctors from Scotland evaluated the long-term effect of weight loss on cholesterol, high- and low-density lipoproteins, and triglycerides in overweight or obese individuals.
The team performed a systematic review of weight loss studies, published between 1966 and 2001.
They assessed all cohort studies and trials which included participants with body mass index of ≥ 28 kg/m.
In addition, the studies had to have at least 2 weight change measurements, and follow-up of more than 2 years.
|For every 10 kg of weight lost a drop in cholesterol of 0.23 mmol/L can be expected.|
The team identified 13 long-term studies which met their inclusion criteria.
They determined that cholesterol has a significant positive linear relationship with weight change (r = 0.89).
The team found that a change in weight explains approximately 80% of the cholesterol variation (Adj R2 = 0.80).
Furthermore, for every 10 kg of weight lost a corresponding drop in cholesterol of 0.23 mmol/L can be expected.
Dr Poobalan's team concluded, "Weight loss has long-term beneficial effects especially on low-density lipoprotein and cholesterol".
"Weight loss in obese patients should be encouraged and sustained".