Percutaneous endoscopic gastrostomy (PEG) is the preferred method for providing enteral nutritional support in patients with dysphagia.
In this study, physicians from Japan examined gastric antral myoelectrical activity and gastric emptying before and after PEG tube placement. The team's aim was to evaluate the effects of PEG on gastric motility.
PEG was performed in 41 patients. Of these, 21 patients were fed by total parenteral nutrition (TPN) and 20 received nasogastric tube feeding (NGF).
|7% of patients developed gastroesophageal reflux after PEG tube placement.|
|Journal of Gastroenterology|
The physicians assessed antral myoelectrical activity and gastric emptying both before and 4 weeks after PEG tube placement.
The team found that the percentage of normal-range electrogastrograms (EGGs) was lower in the TPN group, compared to the NGF group.
They determined that enteral feeding after PEG tube placement improved gastric motility in the patients with TPN.
Furthermore, the percentage of normal-range EGGs increased significantly after PEG tube placement.
The team also found that plasma concentrations of acetaminophen increased significantly after PEG tube placement in patients with TPN.
However, 7% of the patients developed gastroesophageal reflux after PEG tube placement.
The physicians found that gastric myoelectrical activity and gastric emptying were improved in patients with gastroesophageal reflux after PEG tube placement
They also determined that the prevalence of esophageal hiatus hernia was higher in patients with gastroesophageal reflux after PEG tube placement, than in those without.
Dr Hiromi Ono's team concluded, "Enteral nutrition is the preferable physiological nutritional route".
"Gastroesophageal reflux after PEG tube placement is not related to gastric motility".
"Esophageal hiatus hernia seems to be a major risk factor for gastroesophageal reflux complications after PEG tube placement".