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 17 January 2018

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News

Evaluation of a new bioabsorbable self-expanding biliary stent

A new bioabsorbable biliary stent can be deployed endoscopically and remains patent for up to 6 months, find researchers in the latest issue of Gastrointestinal Endoscopy.

News image

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Bioabsorbable stents may offer advantages for the treatment of benign and malignant biliary strictures.

In this study, researchers from Finland and the United States evaluated a new bioabsorbable biliary stent (BioStent) using a porcine model.

The team placed 8 BioStents in animals.
There was no clinical evidence of biliary obstruction.
Gastrointestinal Endoscopy

They assessed the accuracy and ease of delivery and deployment, radial expansion, and radiologic visualization.

They also evaluated stent function and biotolerance using cholangiography, serum bilirubin, and necropsy for histopathology.

The researchers found that the stents were delivered without sphincterotomy. They were easily and accurately deployed. In addition, they had good immediate stent expansion and radiographic visualization.

The team found on follow-up that all stents were fully expanded and serum bilirubin levels were within the normal range.

There was no clinical evidence of biliary obstruction, but the team identified filling defects at cholangiography.

Dr Gregory Ginsberg's team concluded, "The BioStent bioabsorbable biliary stent…can be effectively deployed endoscopically, is self-expanding, is visualized radiographically, and remains patent up to 6 months".

"There was no bile duct integration or proliferative change, which are potential advantages".

"Stent occlusion and migration remain concerns".

Gastrointest Endosc 2003; 58(5):
10 November 2003

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