In this study, physicians from the United States developed a scoring system to predict esophageal findings at endoscopy.
The team evaluated 1011 consecutive adult patients who were scheduled for upper endoscopy.
Patients were asked to complete a validated symptom questionnaire.
|Reflux esophagitis was associated with heartburn frequency.|
The physicians developed logistic regression models to predict esophagitis, Barrett's esophagus, and esophageal stricture.
The team found that reflux esophagitis was associated with heartburn frequency, but not severity or duration. However, Barrett's esophagus was associated with duration, but not with frequency or severity.
In addition, the physicians determined that strictures were associated with dysphagia severity and duration, but not frequency.
At a sensitivity of 80%, specificity for esophagitis was found to be 49%, 57% for Barrett's esophagus, and 68% for strictures.
Furthermore, at a specificity of 80%, sensitivity was 51% for esophagitis, 62% for Barrett's esophagus and 71% for strictures.
Dr Richard Locke's team concluded, "Endoscopic findings were associated with distinct attributes of reflux symptoms".
"Symptoms are only modestly predictive of findings at endoscopy".