In this study, physicians from the United States evaluated epidemiologic and clinical characteristics of newly diagnosed pediatric inflammatory bowel disease (IBD) in a large population.
Pediatric gastroenterologists in the state of Wisconsin, USA, identified all new cases of IBD during a 2-year period.
|89% of new IBD diagnoses were nonfamilial.|
|Journal of Pediatrics|
They sent all demographic and clinical data to a central registry prospectively for analysis.
The physicians found that the incidence of IBD in Wisconsin children was 7.05 per 100,000. The incidence of Crohn's disease was more than twice the rate of ulcerative colitis.
They determined that an equal incidence of IBD occurred among all ethnic groups.
Furthermore, children from sparsely and densely populated counties were equally affected.
The team also determined that 89% of new IBD diagnoses were nonfamilial.
Dr Subra Kugathasan's team concluded, "This study provides novel, prospective, and comprehensive information on pediatric IBD incidence within the United States".
"The surprisingly high incidence of pediatric IBD…suggest[s] that the clinical spectrum of IBD is still evolving and point to environmental factors contributing to the pathogenesis".