In this study, researchers from the United States followed a cohort of children without Helicobacter pylori infection. They compared the growth velocity in children who become infected during follow-up with that of children who remained infection-free.
The team assessed 347 children, aged 12 to 60 months, who tested negative for H. pylori.
Anthropometric measurements were performed every 2 months and breath tests every 4 months.
|Growth velocity was reduced by 0.042 cm per month.|
|Journal of Pediatric Gastroenterology and Nutrition|
The researchers used linear mixed models to analyze growth velocity in relation to the onset of H. pylori infection.
Overall, 30% of the children who were uninfected at the start of the study became infected during follow-up.
The team found that growth velocity in infected children was reduced by 0.042 cm per month, after adjusting for age.
The team established that this rate of deceleration in growth velocity was relatively constant over time.
Dr Luis Eduardo Bravo's team concluded, "Among…children aged 12 to 60 months…a new and sustained [H. pylori] infection was followed by significant growth retardation.