Studies have shown superior long-term survival after curative resection of colon cancer at hospitals where the volume of such surgeries is high. However, these lack information on cancer recurrence.
In this study, investigators from the United States determined whether hospital procedure volume predicts long-term outcomes of colon cancer surgery.
The team assessed 3161 patients with high-risk stage II and stage III colon cancer.
|5-year overall survival differed across tertiles of hospital procedure volume.|
|Annals of Internal Medicine|
They measured overall survival and recurrence-free survival by hospital procedure volume.
The investigators found that 5-year overall survival significantly differed across tertiles of hospital procedure volume.
Once the team adjusted for other predictors of colon cancer outcome, the hazard ratio for overall mortality in patients treated at low-volume centers was 1.16.
However, the doctors determined that the risk for cancer recurrence was not associated with hospital procedure volume. They found that 5-year recurrence-free survival was 64% for patients from low-volume hospitals, compared with 63% for patients from high-volume hospitals.
Dr Jeffrey Meyerhardt's team concluded, "Patients whose colon cancer was resected at low-volume hospitals experienced a higher risk for long-term mortality".
"However, this increased mortality was not attributable to differences in colon cancer recurrences".