In this study, North American investigators evaluated the association between psychosocial characteristics and time to relapse in patients with inactive ulcerative colitis.
They evaluated 60 patients with clinically and endoscopically inactive ulcerative colitis over a 1 year period.
The team obtained demographic, psychosocial, and clinical data.
|27% of patients relapsed during follow-up.|
|American Journal of Gastroenterology|
In addition, patients reported any stressful life events (Psychiatric Epidemiology Research Interview Life Events Scale), psychological distress (Symptom Checklist-90R), and or perceived stress (Perceived Stress Scale).
The team found that 27% of patients relapsed during follow-up.
They identified a weak association between the number of stressful events in the preceding month and time to relapse. This association was strengthened once adjustment was made for significant covariates.
Dr Alain Bitton's team concluded, "After controlling for demographic and clinical variables, more recent stressful events were associated with earlier time to relapse".
"These findings…might help clinicians identify patients who might benefit from more intensive maintenance medical therapy and behavioral medicine interventions to reduce stress and improve coping".