In this study, investigators from Germany investigated the relationship between oral and fecal Candida albicans pre-school age children
The team used RAPD analysis to evaluate 56 patients with severe caries and 52 healthy controls.
|The highest prevalence was in carious specimens.|
|Oral Microbiology and Immunology|
They determined that higher levels of C. albicans occurred in saliva, dental plaque, carious specimens and stools of the cases compared with the controls.
They also found that the highest prevalence was in carious specimens. There was a strong correlation between its presence in saliva, dental plaque, carious specimen and feces.
The investigators also found that of the 23 patients with simultaneous oral and fecal C. albicans 15 had clonal counterparts present in both oral and stool samples. A further 5 patients harbored closely related strains, while 3 patients had unrelated strains.
Dr Hossain's team concluded, "Our results demonstrate a strong correlation between oral and gastrointestinal C. albicans colonization".
"We assume that carious teeth may constitute an ecologic niche for C. albicans potentially responsible for recurrent oral and non-oral candidiasis".