In this study, researchers from the United States determined whether Helicobacter pylori treatment in patients with dyspepsia or peptic ulcer decreases hospital expenditures.
The research team interviewed patients receiving acid suppressive medication.
Any patients with a documented ulcer, a self-reported ulcer, or dyspepsia were tested for H. pylori. These patients were treated with antibiotics if seropositive.
The team stopped acid suppressive medications after H. pylori therapy unless patients had a history of GERD or Barrett’s esophagus.
The researchers then compared the total hospital and medication costs from the 12 months before H. pylori treatment, those 12 months after.
|Costs before H. pylori treatment were no different to those after treatment.|
|American Journal of Gastroenterology|
A total of 432 consecutive patients were treated for H. pylori.
Of the patients, 29% had dyspepsia, 10% documented peptic ulcer, and 61% self-reported peptic ulcer.
The team determined that costs before H. pylori treatment were not significantly different to those after treatment.
However, they identified a significant decrease in costs for patients who were on acid suppressive medications, had documented peptic ulcers, and no history of GERD or Barrett’s esophagus.
Dr David Kearney's team concluded, "Treatment of H. pylori for patients with chronic dyspepsia or self-reported peptic ulcer does not reduce expenditures over 1 year of follow-up".
H. pylori treatment for patients chronically receiving acid suppressive treatment with a prior documented ulcer significantly reduces expenditures if GERD and Barrett’s esophagus are absent".