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 17 January 2018

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News

Cirrhosis as a risk factor for sepsis and death

Cirrhosis is strongly associated with an increased risk of sepsis, find physicians in the latest issue of Chest.

News image

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There have been several reports on the influence of cirrhosis on survival in the critically ill. However, variations in the reports limit the generalization of these data to other institutions.

In this study, physicians from Atlanta, Georgia, evaluated the impact of cirrhosis on the outcome of sepsis, sepsis-related mortality, and respiratory failure in hospitalized patients.

The team used data from the National Hospital Discharge Survey (1995 to 1999). During this period there were 175 million hospital discharges throughout the United States; 1% of these involved a diagnosis of cirrhosis.

The physicians adjusted the data for age, race, and gender.
Cirrhosis is associated with an increased risk of sepsis and death.
Chest

They found that cirrhotic individuals are significantly more likely to die while hospitalized, to have hospitalizations associated with sepsis, and to die from sepsis.

In addition, the team determined that cirrhosis is associated with an increased risk of acute respiratory failure, as well as death from acute respiratory failure.

Dr Marilyn Foreman's team concluded, "A diagnosis of cirrhosis is strongly associated with an increased risk of sepsis, acute respiratory failure, sepsis-related mortality, and acute respiratory failure-related mortality".

Chest 2003; 124: 1016-20
18 September 2003

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