There have been reports of a possible increase of pediatric Crohn’s disease.
In this study, physicians from Stockholm, Sweden, assessed the incidence and characteristics of inflammatory bowel disease (IBD) in northern Stockholm between 1990 and 2001.
The team evaluated all records of patients aged 0 to 15 years with suspected IBD, from an area with a population of 180,000.
They searched patient files for relatives with IBD, and for concomitant autoimmune diseases.
The physicians found that a total of 152 children were diagnosed with IBD. This was an overall incidence of 7.4 children with IBD per 100,000. The incidence of Crohn’s disease (CD) was 4.9, ulcerative colitis (UC) 2.2, and indeterminate colitis 0.2.
The team found that, between 1990 and 2001, there was an increase in the incidence of CD, while the incidence of UC was almost unchanged. Overall, they identified a net increase in the occurrence of IBD.
The team also found that there was a male dominance of CD.
|There is an overall incidence of 7.4 children with IBD per 100,000.|
They determined that 14% of patients with CD and 11% of patients with had a first or second degree relative with IBD.
In addition, 18% of patients with CD and 10% of patients with UC had a concomitant autoimmune disease.
Dr Hildebrand's team concluded, "The incidence of CD has increased in northern Stockholm".
"The current incidence is higher than that reported from other areas".
"Our results suggest a shift in presentation and diagnosis from UC towards CD, but also a net increase in IBD".
"Concomitant autoimmune disorders and family history are common in pediatric IBD".