In patients with colorectal cancer, their health-related quality of life (HRQL) after treatment is a combination of a number of factors. These include preexisting medical conditions, disease burden, and type of treatment.
In this study, doctors from Dallas, Texas, identified the factors associated with post-treatment HRQL.
Patients completed a colorectal cancer-specific HRQL survey (FACT-C), both at baseline and at 12 months after diagnosis.
The research team used univariate and multivariate analyses to identify variables associated with the 12-month FACT-C total scores.
|Perioperative complications are associated with reduced 12-month survey scores.|
Overall, 71 patients completed the survey at diagnosis, and underwent open surgical removal of their primary tumor.
Of these 71 patients, 63 completed the 12-month survey.
Univariate analysis showed that only chronic obstructive pulmonary disease at diagnosis, or perioperative complications were associated with reduced 12-month survey scores.
However, on multivariate analysis only the perioperative complications and FACT-C total score at diagnosis were associated with a lower score at 12 months.
Dr Thomas Anthony's team concluded, "For patients who undergo treatment of colorectal cancer, HRQL at 1 year after diagnosis is still influenced significantly and negatively by the occurrence of surgical complications".