Older age is not considered a contraindication for liver transplantation.
A team of Doctors in Spain reviewed 111 liver transplants to compare the survival of patients over 60 years old who undergo liver transplantation with the survival of younger patients.
They also investigated any factors involved in a potential difference in mortality.
Of the 111 patients analysed 54 were older than 60 years of age and 57 were younger.
| After transplantation, older patients had a significantly lower survival. |
|American Journal of Transplantation|
After transplantation, older patients had a significantly lower survival. Higher age was associated with increased mortality independent of other variables.
The incidence of de novo neoplasia and nonskin neoplasia was significantly higher in older patients.
Malignancy was the cause of death in 12 patients older than 60 years, but only 1 patient younger than 60 years.
Higher age as well as smoking were significantly associated with the incidence death due to de novo neoplasia.
Increased frequency of malignancy in older transplant patients appears to lead to increased mortality.