Peptic ulcer perforation leads to high complication and mortality rates. Surgery is commonly used to treat the problem.
Surgical intervention can be directed to treating the perforation alone or it can offer definitive treatment of the ulcer itself.
A team of surgeons in Portugal compared the outcomes of the different means of surgical intervention and evaluated the main risk factors for the morbidity and mortality associated with surgery.
210 patients who underwent surgery for perforated peptic ulcer were followed in the study.
Resections were performed in 10 patients, 88 patients were treated by suturing the perforation, and 112 underwent definitive surgery to treat the ulcer with a troncular vagotomy and drainage.
10% of the patients died after surgery.
There was no significant difference concerning morbidity and mortality between simple closure of the perforation and definitive surgery.
Significant risk factors that led to complications after surgery were a perforation that had been present more than 24 hours, coexistence of significant associated illnesses, and resection surgery.
| There was no difference in mortality between simple closure of the perforation and definitive surgery to eradicate the ulcer.|
|World Journal of Surgery|
Risk factors for mortality were presence of shock at admission, coexistence of significant illnesses, and resection surgery.