A team from the Huddinge University Hospital, Huddinge, Sweden assessed the risk for resection and postoperative recurrence in the treatment of ileocaecal Crohn's disease. They also defined factors affecting the course of the disease.
A cohort of 907 patients with primary ileocaecal Crohn's disease was reviewed retrospectively.
Ileocaecal Crohn's disease resection rates: 61%, 77%,and 83% at 1, 5, and 10 years, respectively.
Resection rates were 61 per cent, 77 per cent, and 83 per cent at 1, 5, and 10 years, respectively, after the diagnosis. Relapse rates were 28 per cent and 36 per cent, 5 and 10 years after the first resection.
The team found that a younger age at diagnosis resulted in a lower resection rate.
The presence of perianal Crohn's disease and long resection segments increased the incidence of recurrence; and resection for a palpable mass and/or abscess decreased the recurrence rate.
During the study period (1955-1989), a decrease in recurrence rate was observed.
In ileocaecal Crohn's disease the probability of resection is high, and the risk of recurrence moderate, it was reported.
Crohn's disease in childhood carries a lower risk of primary resection. Perianal disease and extensive ileal resection increase the risk of recurrence, the group concluded.