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 24 May 2018

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News

Radical prostatectomy for locally advanced primary or recurrent rectal cancer

In spite of a relatively high urinary leak rate the total complication rate for radical prostatectomy appears to be lower than after pelvic exenteration, find researchers in the June issue of the European Journal of Surgical Oncology.

News image

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Previous papers have described en bloc radical prostatectomy for locally advanced rectal cancer.

In this study, researchers from Norway assessed 6 patients (median age 63 years) who underwent en bloc radical prostatectomy for locally advanced or recurrent rectal cancer involving the prostate.

The patients answered quality of life questionnaires postoperatively. Their answers were entered in a database.

Of the 6 patients, 1 had low anterior resection, while the others had abdominoperineal resections (APR) of R0 stage.

4 of the 5 patients with anastomoses had good quality of life.
European Journal of Surgical Oncology

There were 2 recurrent cases who had APRs, as well as 1 tumor resection. All of these were R1 stage.

The team found that anastomotic leakage led to construction of an ileal conduit in 1 patient, however, in 2 this healed with conservative management.

The average length of follow-up was 10 to 50 months.

The researchers found that 1 patient died from distant metastases at 29 months postoperatively. A further patient was operated for a single lung metastasis, and 1 developed disseminated lung metastases.

Overall, the team determined that no patient developed local recurrence.

Furthermore, 4 of the 5 patients with anastomoses had good quality of life. None of these patients wanted an ileal conduit.

Dr Wiig's team concluded, "In spite of a relatively high urinary leak rate the total complication rate seems to be lower than after pelvic exenteration".

"En bloc radical prostatectomy seems an option in selected patients otherwise needing pelvic exenteration for locally advanced or recurrent rectal cancer".

Eur J Surg Oncol 2003; 29(5): 455-8
14 July 2003

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