Researchers from Brazil investigated the influence of reduction in intra-abdominal pressure on lower esophageal sphincter pressure (LESP), and on 24-hour pH monitoring.
They examined 16 patients with ascites, before and after paracentesis.
|Lower esophageal sphincter pressure did not change with the reduction of intra-abdominal pressure.|
|Diseases of the Esophagus|
The team found that LESP did not change with the reduction of intra-abdominal pressure.
They divided results into 2 groups according to the achieved reduction in intra-abdominal pressure. Group A were patients who had a reduction greater than 70%. Group B had a reduction of less than 70%.
The researchers determined that LESP did not change even when the groups were analyzed separately.
However, the team observed that the 24-h pH monitoring showed pathological reflux in patients with ascites, which was reduced with the paracentesis.
They determined that all pH-monitoring parameters were statistically different, both before and after the reduction of intra-abdominal pressure in group A, but not group B.
Dr Navarro-Rodriguez's team concluded that, "LESP does not change significantly when the intra-abdominal pressure is significantly reduced".
"Patients with ascites showed gastroesophageal reflux".
"Intra-abdominal pressure reduction greater than 70% lead to a significant reduction in gastroesophageal reflux".