Differential diagnosis in pancreatic cystic lesions is often difficult, despite the use of modern imaging.
In this study, researchers assessed the role of EUS in several situations:
- Discrimination of pseudocysts from pancreatic cystic tumors
- Differential diagnosis between serous cystadenoma and mucinous cystic tumor
- Prediction of accompanying malignancy in intraductal papillary mucinous tumor.
They evaluated EUS findings in 75 patients with pancreatic cystic lesions (58 cystic tumors, 17 pseudocysts).
Their results are published in the June issue of Gastrointestinal Endoscopy.
|Septa and mural nodules were found more frequently in cystic tumors than pseudocysts.|
The team found that pseudocysts exhibited echogenic debris and parenchymal changes more often than cystic tumors
However, septa and mural nodules were found more frequently in cystic tumors than pseudocysts.
The team also determined that parenchymal changes, septa, and mural nodules were independent predictors of differentiation between pseudocysts and cystic tumors.
In addition, they found that serous cystadenoma exhibited diverse EUS features, plus a honeycomb appearance.
Mural nodules were found more often in mucinous cystic tumors than in serous cystadenomas.
The researchers were unable to identify factors that predicted malignancy in intraductal papillary mucinous tumor.
Dr Moon Hee Song's team concluded, "EUS is a useful complementary imaging method for differentiation of pancreatic cystic lesions".