The Model for End-Stage Liver Disease (MELD) is an important predictor in patients awaiting orthotopic liver transplantation (OLT).
However, the model's ability to predict post-transplant patient survival is unclear.
|Patient survival was poorer with higher MELD scores.|
In this study, researchers from Los Angeles, California, studied 1-year patient survival in 404 adults who had undergone OLT.
The team calculated survival hazard rates according to the MELD strata and United Network for Organ Sharing (UNOS) status, using Cox regression analysis.
Survival differences for MELD strata and UNOS status were also compared.
The team identified a significant difference in 1-year patient survival using different MELD strata.
They found an increased rate of death patients with higher MELD scores, and more urgent UNOS status.
Dr Sammy Saab's team concluded, "The MELD stratum is better associated with 1-year patient survival in liver transplant recipients than UNOS statuses".
"Patient survival was worse with higher MELD scores".