In this study, researchers assessed the long-term outcomes of patients who had endoscopic balloon dilation of Crohn's strictures.
The research team's findings are published in the May issue of the European Journal of Gastroenterology and Hepatology.
|41% of patients achieved long-term clinical benefit following dilation.|
|European Journal of Gastroenterology and Hepatology|
The team performed a retrospective case-note review over a 16-year period.
They identified 59 patients with Crohn's strictures who underwent endoscopic balloon dilation. Patients had a minimum of 6 months follow-up data, or a surgical outcome following dilation.
The team found that strictures were anastomotic in 53 patients (111 dilations) and de novo in 6 patients (13 dilations).
Median stricture length was 3 cm and median follow-up time was 29.4 months.
The researchers determined that of the total group, 41% of patients achieved long-term clinical benefit following dilation. Benefit was achieved in 17% after only a single dilation.
Overall, 59% patients required surgery for their stricture during follow-up.
The team determined that there were 2 perforations as a result of dilation, 1 in an anastomotic stricture and 1 in a de-novo stricture.
There were no deaths.
Dr Siwan Thomas-Gibson's team concluded, "Colonoscopic balloon dilation of Crohn's strictures can achieve long-term clinical benefit in many patients".
"Repeat dilations are justified in initial non-responders".
"In this series, the procedure appears safe with low morbidity".