In this study, researchers from the United States systematically reviewed research on the prevalence of abdominal and pelvic surgery in patients with irritable bowel syndrome.
They performed computer searches of MEDLINE, EMBASE and Current Contents in order to identify appropriate studies.
The team's primary study selection criteria included:
- Population-based samples of adult irritable bowel syndrome patients
- The use of appropriate symptom-based criteria to identify irritable bowel syndrome patients, and
- Comparison of the prevalence of abdominal and pelvic surgery in irritable bowel syndrome patients versus control populations.
The team also performed a secondary analysis on published studies of referral populations and case series.
|Secondary analysis revealed an increased prevalence of appendectomy.|
|Alimentary Pharmacology and Therapeutics|
The team found 2 population-based studies met the primary study selection criteria. They revealed an increased prevalence of surgery in irritable bowel syndrome patients compared with controls for cholecystectomy (5% versus 2%, respectively) and hysterectomy (18% versus 12%).
Secondary analysis revealed an increased prevalence of appendectomy, and other abdominal and pelvic surgery in irritable bowel syndrome patients.
Drs Hasler and Schoenfeld concluded, "Irritable bowel syndrome is associated with a disproportionately high prevalence of abdominal and pelvic surgery".
However, "Most studies exhibit sub-optimal study design and do not define the factors causing the increased prevalence of surgery in these patients".