In this study, researchers from Japan assessed the incidence of colorectal cancer in relation to body size, smoking, and alcohol consumption.
The team studied in a cohort of 29,051 city residents.
Each participant completed a questionnaire on sociodemographic characteristics, drinking, cigarette smoking, diet, exercise, and reproductive and medical histories in 1992.
The response rate was 92%.
|BMI positively associated with colon cancer risk for men.|
|British Journal of Cancer|
There were 161 men and 134 women diagnosed with colorectal cancer at 2 major hospitals in the city, between 1993 and 2000.
The team calculated relative risks and 95% confidence intervals using Cox proportional hazard models.
The researchers found a positive relation between height and colorectal cancer in both sexes, when controlling for age, BMI, smoking and drinking habits, and education.
However, findings were significant for men only (relative risk 2.13 for the tallest compared with the shortest height tertile).
The team also determined that BMI was positively associated with colon cancer risk for men. The pattern for women was not clear.
In addition, there was a positive association between pack-years of cigarette smoking and the risk of rectal cancer in men.
Dr Shimizu’s team also found, “A positive dose-response relation between alcohol consumption and colon cancer risk was observed for men and women”.