Liver metastasis from colorectal cancer remains an oncological challenge.
Hepatic chemotherapy is sometimes used, but its impact on quality of life (QOL) has not been quantified.
In this study, researchers from California, USA, assessed QOL issues in this population.
The research team identified 16 patients treated with intrahepatic chemotherapy.
|Patients had significantly lower scores for psychological, social, and spiritual parameters.|
|Annals of Surgical Oncology|
Consenting patients completed a demographic tool and a QOL survey.
The team also conducted an in-depth interview on QOL concerns. The data from the interviews were coded to identify recurrent themes.
The team found that patients had significantly lower scores for psychological, social, and spiritual parameters, when compared with those of healthy volunteers.
Overall, patients found intrahepatic chemotherapy convenient but were unable to pursue vigorous activity, and their sleep habits changed.
However, patients were reassured by receiving specific liver therapy.
Dr Sarah Blair's team concluded, "Pilot evaluation of QOL in this population revealed changes in physical, psychological, social, and spiritual dimensions".
"Both disease- and treatment-specific concerns were identified, and the results provide evidence for items to include in a QOL questionnaire specific to this population."