The small bowel is the most commonly affected site of Crohn's disease (CD), although it may involve any part of the gastrointestinal tract.
The current methodologies for examining the small bowel are X ray and endoscopy.
In this study, researchers from Israel evaluated the effectiveness of wireless capsule endoscopy in patients with suspected CD of the small bowel. They reviewed patients where CD had been undetected by conventional modalities and determined the diagnostic yield of the M2A Given Capsule.
The research team assessed 17 patients (8 males, mean age 40 years) with suspected CD.
Of these patients, 9 had iron deficiency anemia, 8 had abdominal pain, 7 had diarrhoea, and 3 had weight loss.
The patient's small bowel X ray, and upper and lower gastrointestinal endoscopic findings were normal.
|12 of 17 patients diagnosed with Crohn's disease using wireless capsule endoscopy.|
The mean duration of symptoms before diagnosis was 6.3 years.
Each subject swallowed an M2A Given Capsule containing a miniature video camera, batteries, a transmitter, and an antenna. Recording time was approximately eight hours.
The capsule was excreted naturally in the patient's bowel movement.
The team retrieved and interpreted the data it contained the next day.
Of the 17 patients in the study, the team diagnosed 12 as having CD of the small bowel according to the findings of the M2A Given Capsule.
Dr Fireman's team concluded that wireless capsule endoscopy was "an effective modality for diagnosing patients with suspected CD undetected by conventional diagnostic methodologies".