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 24 November 2017

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News

H. pylori colonization related to lower incidence of diarrheal diseases in children

Gastric colonization by Helicobacter pylori is associated with a lower incidence of diarrheal diseases amongst children, according to a report in the November issue of the Journal of Infectious Diseases.

News image

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A multidisciplinary team, based in Ulm, Germany, compared the rates of diarrheal illnesses in H. pylori-positive and H. pylori-negative children.

Children included in the study were routinely screened for school fitness in Ulm, during 1996-1998. 2477 five to eight-year-old children were monitored. Of these, 12.3 per cent were found to be H. pylori-positive, as shown by a carbon 13-labeled urea breath test.

Diarrhea occurrence:
H. pylori-positive 54.3%
H. pylori-negative 76.1%

For H. pylori-positive children, diarrhea within the prior 3 months was less often reported than for H. pylori-negative children (54.3 per cent vs. 76.1 per cent).

Compared with H. pylori-negative children, the odds ratio (OR) for the occurrence of diarrhea within the prior 3 months was 0.37 for H. pylori-positive children. After adjustment for co-variates, the OR was 0.56.

Dr Dietrich Rothenbacher concluded on behalf of the group that, "Data from this population-based cross-sectional study supports the hypothesis that H. pylori colonization may protect against diarrheagenic gastrointestinal infections."

J Infect Dis 2000; 182: 1446-1449
28 November 2000

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