A multidisciplinary team, based in Ulm, Germany, compared the rates of
diarrheal illnesses in H. pylori-positive and H. pylori-negative
Children included in the study were routinely screened for school
fitness in Ulm, during 1996-1998. 2477 five to eight-year-old children
were monitored. Of these, 12.3 per cent were found to be H. pylori-positive, as
shown by a carbon 13-labeled urea breath test.
H. pylori-positive 54.3%
H. pylori-negative 76.1%
For H. pylori-positive children, diarrhea within the prior 3 months was
less often reported than for H. pylori-negative children (54.3 per cent vs.
76.1 per cent).
Compared with H. pylori-negative children, the odds ratio (OR) for the
occurrence of diarrhea within the prior 3 months was 0.37 for H. pylori-positive children. After adjustment for co-variates, the OR was 0.56.
Dr Dietrich Rothenbacher concluded on behalf of the group that, "Data
from this population-based cross-sectional study supports the hypothesis
that H. pylori colonization may protect against diarrheagenic gastrointestinal infections."