It has been suggested that symptoms from bile reflux gastritis are related to the frequency and degree of enterogastric reflux (EGR).
In this study, a research team from Greece and the United States assessed patients with history of upper GI surgery, or cholecystectomy, plus control patients.
The team determined the presence of EGR, degree of EGR, and gastric bile emptying time via 99mTC scintillation imaging.
|Asymptomatic and symptomatic patients showed a statistically significant difference in gastric emptying time.|
|American Journal of Surgery|
They then compared between symptomatic and asymptomatic patients.
The researchers found that patients with vagotomy and pyloroplasty, Billroth I, Billroth II, and cholecystectomy had statistically higher degrees of EGR, compared with controls.
The team found that asymptomatic and symptomatic patients showed a statistically significant difference in gastric emptying time.
However, no differences were found between the groups for incidence of EGR and degree of EGR.
Dr Anastasia Stavraka's team concluded, "Delayed gastric emptying time, not frequency or extent of EGR, was associated with the symptoms of bile reflux in patients who had previous upper gastrointestinal or biliary operations".