In this study, researchers from Europe and the United States assessed the relationship between coffee consumption and hepatocellular carcinoma.
The team updated and reanalyzed 2 previous studies from Italy and Greece in order to clarify the role of coffee consumption.
The combined number of subjects, from the 2 previous studies, included 834 cases of hepatocellular carcinoma and 1912 controls.
The team found that when compared to non-coffee drinkers, the odds ratio for coffee drinkers was 0.8. This value was 0.6 for drinkers of 3 or more cups per day.
However, once allowances were made for alcohol consumption, smoking and other factors, these figures became 1 and 0.7, respectively.
| Inverse relationship between coffee consumption and hepatocellular cancer consistent between the 2 datasets.
|British Journal of Cancer|
Furthermore, the research team discovered that the inverse relationship, between coffee consumption and hepatocellular cancer, was consistent between the 2 datasets.
Dr Gallus's team concluded, "The present study confirms in a large dataset, the hypothesis of an inverse association between coffee drinking and liver cancer".
"However, the interpretation of this association and the consequent inference on causality remains open".