Bovine colostrum is a rich source of nutrients, antibodies and growth factors.
In this study, a research team from England examined the efficacy of colostrum enemas in the treatment of distal colitis.
They used a randomized, double-blind, controlled protocol.
The team examined 14 patients (8 female, mean age 45 years) with mild to moderately severe distal colitis.
|Patients showing histological improvement:|
- Colostrum group = 63%
- Placebo group = 33%
|Alimentary Pharmacology and Therapeutics|
Patients received either colostrum enema (100 ml of 10% solution) or placebo (albumin solution) for 4 weeks.
Both groups also received mesalazine (1.6 g per day) or, if already taking it, a dose increment of 1.6 g per day.
The team documented disease activity at 0, 2 and 4 weeks.
The researchers identified a mean reduction in symptom score of -2.9 in the colostrum group, after 4 weeks. Whereas, the placebo group showed a mean response of +0.5.
In addition, histological scores improved in 63% of patients in the colostrum group, whereas they only improved in 33% of patients in the placebo group.
Dr Khan's team concluded, "Bovine colostrum enema shows potential as a novel therapy for left-sided colitis with additional benefits over using mesalazine alone".
"Further studies appear to be warranted".