HCC is an epithelial tumor derived from hepatocytes that accounts for more than 80% of all primary hepatic tumors.
The severity of the underlying disease is almost always the key factor in deciding whether to consider liver resection or transplantation as its treatment.
The registry comprises of almost 800 patients from transplant centers throughout the world.
|Factors affecting patient survival after transplantation:|
- Histologic grade
- Tumor size > 5 cm
- Presence of positive nodes
| Liver Transplantation |
Reporting in September's Liver Transplantation, the authors found that histologic grade, tumor size > 5 cm, and the presence of positive nodes significantly affected patient survival after liver transplantation.
Recurrence-free survival showed a correlation with tumor size > 5 cm, positive nodes, bilobar spread, and vascular invasion.
At the time of the study, 59% of patients in the authors' registry were alive, 84% of whom were free of tumor.
Of those who died, half did so without evidence of tumor.