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 22 November 2017

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News

Dye-spray increases detection of small adenomas during routine colonoscopy

Total colonic dye-spray increases the detection of small adenomas in the proximal colon and also patients with multiple adenomas, claims a team from London, England.

News image

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The researchers determined the effect of total colonic dye spray on adenoma detection during routine colonoscopy, and reported their findings in the September issue of Gastrointestinal Endoscopy.

A total of 259 consecutive outpatients undergoing routine colonoscopy were enrolled in the trial.

They were randomized to a dye-spray group (0.1% indigo carmine used to coat the entire colon during withdrawal from the cecum, n = 124) or control group (no dye, n = 135).

Demographics, indication for colonoscopy, and quality of the preparation were similar between the groups.

Dye-spray identified more:
- Diminutive adenomas
- Patients with ≥ 3 adenomas
- Non-neoplastic polyps
Gastrointestinal Endoscopy
Extubation from the cecum took a median of 9.0 minutes in the dye-spray group versus 4.5 minutes in the control group.

The investigators found that the proportion of patients with at least 1 adenoma and the total number of adenomas were not different between groups.

However, in the dye-spray group significantly more diminutive adenomas (< 5 mm) were detected proximal to the sigmoid colon. In addition, more patients were identified with 3 or more adenomas.

Furthermore, more non-neoplastic polyps were detected throughout the colon in the dye-spray group.

There were no complications reported.

Author Jim C. Brooker, of St Mark's Hospital, London, concluded on behalf of his group, "Dye-spray increases the detection of small adenomas in the proximal colon and patients with multiple adenomas.

"However, long-term outcomes should be studied to determine the clinical value of these findings."

Gastrointest Endosc 2002; 56: 333-8
30 August 2002

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