A study reported in the Journal of the Royal College of Physicians of London suggests that BAM is a much more common cause of diarrhea than is generally thought.
Researchers from Rotherham General Hospital, Yorkshire, UK, studied 304 patients in four groups.
A group of 197 patients had irritable bowel syndrome and BAM was diagnosed in one third of these. 70 per cent responded to treatment with bile acid sequestrants (BAS).
Two groups of patients had Crohn's disease in remission. One group had undergone ileal resection. 97 per cent suffered from BAM and 60 per cent of these responded to treatment with bile acid sequestrants.
Bile acid malabsorption was diagnosed in between 33% and 97% of cases of chronic diarrhea - dependent on other factors.
The second group had not received surgery and 54 per cent had the problem. Treatment helped 40 per cent.
The fourth group to be studied was 24 patients who had undergone gastric surgery and, in some cases, cholecystectomy. 64 per cent responded to treatment.
The researchers, led by clinical scientist Dr Michael Smith and gastroenterology fellow Pradip Cherian, used a selenium-75 labelled homolochic acid conjugated with taurin test to identify BAM.
They write: "When conventional anti-inflammatory and anti-diarrheal drugs fail in such patients, BAS are often effective and improve the quality of life."
Report Copyright: Englemed Health News at http://www.internationalmedicalnews.com