The researchers investigated the use of flexible sigmoidoscopy screening for colorectal neoplasia in average-risk people.
They determined the prevalence of neoplasia detected by re-screening people 5 years after the initial flexible sigmoidoscopy, and reported the findings in the Medical Journal of Australia.
People aged 55-64 years, with no symptoms or family history of colorectal cancer, who were recruited from the community for flexible sigmoidoscopy screening 5 years previously were included in the study.
All originally had no colorectal neoplasms detected.
The number and size of colorectal neoplasms, compared between re-screened patients and the initial screening population (n = 982), were assessed.
A total of 803 people were eligible for re-screening; 138 were no longer at the recorded address, and 361 of the remaining 665 (54%) were re-screened.
|Prevalence of colorectal adenomas:|
Initial screening: 14%
| Medical Journal of Australia |
Re-screening found a significantly lower prevalence of colorectal adenomas than initial screening (8% versus 14%).
The authors also found a lower percentage of adenomatous polyps over 5 mm in diameter (32% versus 51%).
Cameron F. E. Platell, of the University of Western Australia at Fremantle Hospital, Fremantle, concluded on behalf of fellow authors, "Average-risk people who have been screened for colorectal neoplasms, with none found, have a low prevalence of neoplastic lesions 5 years later.
"Longer re-screening intervals need to be considered."