The researchers assessed whether treatment with Lactobacillus improves clinical outcomes in children with acute infectious diarrhea.
The findings of the study were published in the April issue of Pediatrics.
In the meta-analysis, all relevant literature published from 1966 to 2000 was searched.
The authors reviewed 9 of the studies that were identified.
They found that Lactobacillus shortened the duration of diarrhea by two-thirds of a day, compared with those who received placebo.
|Lactobacillus shortened diarrhea duration by two-thirds of a day.
| Pediatrics |
Lactobacillus also reduced diarrhea frequency to 1.6 stools on day 2 of treatment.
The researchers also conducted a preplanned subanalysis, which suggested a dose-effect relationship.
Dr Cornelius W. Van Niel, of the Sea Mar Community Health Center, Seattle, Washington, concluded on behalf of the group, "The results of this meta-analysis suggest that Lactobacillus is safe and effective as a treatment for children with acute infectious diarrhea."