Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 25 May 2018

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Wireless capsule endoscopy is feasible and safe in clinical practice

The clinical use of wireless capsule endoscopy is feasible, safe, and well tolerated, claim researchers reporting to the BSG conference.

News image

fiogf49gjkf04

Researchers from the Royal London Hospital in London, England, assessed the use of wireless capsule endoscopy in two clinical studies.

They reported their findings to the Annual Meeting of the British Society of Gastroenterology, held in Birmingham, England.

In the first study, 38 volunteers and patients referred with obscure gastrointestinal bleeding were included. Colonic views were obtained during clinical studies of capsules with a 7.5-hour life.

From the studies performed, interpretable images of the human colon were acquired in 35, mucosal detail was seen in 34, fecal material in 35, and there was underillumination in 10.

Technical improvements included shorter capsules (27mm, previously 33mm), transmitting for 7-8 hours using 2 (previously 3) batteries. Experimental capsules with a 12-hour life were also tested.

Clinical studies in 13 patients revealed missed colon cancer/polyp (3), bleeding Meckel's diverticulum (1), ulcerative colitis (2), and angiodysplasia (2).

The team found that capsules used in patients with incomplete colonoscopies provided useful clinical information. Management was altered in 50% of patients who underwent capsule colonoscopy.

Author M. Mylonaki and colleagues commented that wireless capsule colonoscopy is feasible and has already delivered valuable information in clinical studies.

"Technical development, and better preparation and control over colonic motility are required to extend the range and improve the images of the colon in patients", they said.

"Capsule colonoscopy was a useful adjunct to conventional colonoscopy, especially in patients with difficult recurrent bleeding or incomplete colonoscopy," they concluded.

All patients preferred capsule endoscopy to push-enteroscopy.
BSG
In the second study, clinical efficacy and technical performance of wireless capsule endoscopy was assessed in a series of 55 patients. In a subset of 38 patients, push-enteroscopy was compared with capsule endoscopy.

A bleeding source was discovered in the small intestine in 21 of 38 patients (55%). These included angiodysplasia (11), fresh blood (5), ileal ulcer (1), tumor (2), Meckel's diverticulum (1), and vasculitis (1).

The researchers observed active intestinal bleeding in 3 patients.

No additional intestinal diagnoses were made by enteroscopy.

The yield of push-enteroscopy in evaluating obscure bleeding was 30%.

The capsule found significantly more intestinal bleeding abnormalities than push-enteroscopy. A source of bleeding was identified beyond the reach of the push enteroscope in 9/21 (42%).

Therapy was altered in 50% of patients. In 3 patients, who had required more than 100 units of blood, directed surgery cured (2) or markedly reduced (1) the bleeding.

Furthermore, it was found that patients always preferred capsule endoscopy to push-enteroscopy, and there were no complications.

The team commented that the study showed that capsule endoscopy provides small intestinal imaging comparable to push-enteroscopy and can diagnose intestinal bleeding at sites beyond the reach of push-enteroscopes.

They concluded that the procedure was safe and well tolerated.

BSG
19 March 2002

Go to top of page Email this page Email this page to a colleague

 25 May 2018 
Colorectal cancer–specific mortality
 25 May 2018 
Technology to increase colorectal cancer screening
 25 May 2018 
Post‐operative complications in elderly IBD
 24 May 2018 
Patient-reported outcome measures in IBD trials
 24 May 2018 
Alcohol consumption and outcomes in drug-induced liver injury
 24 May 2018 
Precision medicine for tumors
 23 May 2018 
Management of perianal fistulas in Crohn’s disease
 23 May 2018 
Cardiovascular risk in diabetes mellitus with NAFLD
 23 May 2018 
High body mass index is and ulcerative colitis
 22 May 2018 
Worldwide H.pylori prevalence
 22 May 2018 
PPI and risk of stroke
 22 May 2018 
Online tool predicts bowel dysfunction severity prior to anterior resection
 21 May 2018 
Depressive symptoms in IBD youth
 21 May 2018 
PPI use and cognitive decline
 21 May 2018 
Fecal incontinence and quality of life in IBD
 18 May 2018 
Esophageal dilatation in clinical practice 
 17 May 2018 
IBD and later extraintestinal manifestations
 17 May 2018 
Repeat stool DNA testing
 17 May 2018 
IBS and chronic fatigue following GI infection
 16 May 2018 
Factors associated with fecal incontinence
 16 May 2018 
Diagnostic delay in Crohn's disease
 16 May 2018 
Cardiovascular risk in diabetes mellitus with NAFLD
 15 May 2018 
Guidelines for management of Crohn's
 15 May 2018 
Hep B in the Grey Zone
 15 May 2018 
New therapies for CDI
 14 May 2018 
Blood test for the diagnosis of fibrotic NASH
 14 May 2018 
Outcomes at bariatric centers of excellence
 14 May 2018 
Management of perianal fistulas in Crohn’s
 11 May 2018 
Detection of undiagnosed celiac disease
 11 May 2018 
Alcohol consumption and drug-induced liver injury
 10 May 2018 
Colorectal cancer screening
 10 May 2018 
Fibrosis in patients with chronic hepatitis B
 09 May 2018 
Fecal incontinence
 09 May 2018 
Health problems and IBS
 09 May 2018 
Esophageal dilatation in clinical practice 
 07 May 2018 
Omitting antibiotics in uncomplicated acute diverticulitis
 07 May 2018 
Health problems and IBS
 07 May 2018 
Assessment of diminutive colorectal polyps
 04 May 2018 
National Institutes of Health workshop and obesity
 04 May 2018 
Factors associated with fecal incontinence
 04 May 2018 
Colorectal cancer screening and ethnic inequities
 03 May 2018 
Gastrointestinal ultrasound in IBD
 03 May 2018 
Ultransonography in postsurgical recurrence in Crohn's
 02 May 2018 
Symptom assessment in cirrhotic ascites
 02 May 2018 
Hep C antiviral treatment and liver cancer risk
 02 May 2018 
Chronic Hep B
 01 May 2018 
European guidelines on pancreatic cystic neoplasms
 01 May 2018 
Interferon‐free regimens in Hep C
 01 May 2018 
Age at IBD onset and extraintestinal complications
 30 April 2018 
Formula for preterm infants
 30 April 2018 
Primary antibiotic resistance and sequential therapy for H. pylori
 27 April 2018 
Eastern and western practices for endoscopic resection of colorectal lesions
 27 April 2018 
Anxiety scale for chronic esophageal disease
 27 April 2018 
Disease activity in eosinophilic esophagitis
 26 April 2018 
Obesity and physical activity in diverticulosis
 26 April 2018 
Primary sclerosing cholangitis in the USA
 25 April 2018 
Aspirin and pancreatic cancer
 25 April 2018 
Central mediators of irinotecan-induced steatohepatitis
 25 April 2018 
Neuroimaging in Hep C
 24 April 2018 
Scoring system identifies cancer risk in Barrett's

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2018 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us