“Weekend effect” refers to worse outcomes among patients presenting to the hospital on weekends or holidays.
Dr Ashutosh Gupta and colleagues from Texas, USA performed a systematic review and meta-analysis of observational studies assessing the impact of the “weekend effect” in patients with upper gastrointestinal hemorrhage (UGIH).
The team searched key bibliographic databases using keywords and MeSH terms related to gastrointestinal hemorrhage and “weekend effect”. Our primary analysis evaluated mortality in patients with UGIH who were hospitalized on the weekend or after-hours compared with a weekday.
Secondary outcomes included need for definitive therapy and length of hospital stay.
Relevant data were extracted and meta-analyses were performed using random effects model.
|There was no effect of weekend admission on any of our secondary outcomes|
|American Journal of Gastroenterology|
Subgroup sensitivity analyses were also performed to assess the effects of key variables.
The researchers found that a total of 21 of 224 studies met inclusion criteria.
Overall, the team observed no association between weekend admission and mortality among patients with UGIH.
However, meta-analysis using only the 9 studies that did not report having a weekend rounder showed a significant increase in mortality.
The research team noted no effect of weekend admission on any of our secondary outcomes.
Dr Gupta's team comments, "Current evidence suggests that weekend admission is associated with significant increase in mortality in patients with non-variceal UGIH but no difference in mortality was noted in patients with variceal UGIH."
"Our findings are relevant to policymakers, practitioners and providers who should ensure the creation of consistent quality and access to care throughout the week."