There are inconsistent reports on age-related differences in inflammatory bowel disease (IBD).
On the basis of patient information, Dr Antjea Timmer and colleagues described the clinical presentation and therapy in relation to age at diagnosis in longstanding pediatric IBD.
Two surveys were conducted in children and young adults by pretested postal questionnaires.
The main analyses are descriptive, showing proportions and distributions per grouped age of diagnosis.
|61% of patients reported feeling currenty well|
|European Journal of Gastroenterology & Hepatology|
Recent disease course, use of biological therapy, and resecting surgery were chosen as indicators of disease severity.
Patients with a diagnosis in infancy are presented as a case series.
The research team reported that information of 1280 cases was available.
The researchers noted that stable remission during the preceding year was reported by 57% of patients.
The team found that 61% of patients reported feeling currenty well.
Anti-tumor necrosis factor therapy was reported by 33% of CD patients, and 9% of UC patients, immunomodulation in 82% and 63%, and corticosteroids by 78% and 76%, respectively.
The researchers observed that age at diagnosis was not associated with indicators of severe disease.
Diagnosis in infancy was reported by 37 patients.
Dr Timmer's team concludes, "Our data do not support age at diagnosis-related differences in prognosis in pediatric-onset IBD."