Previous literature has shown that propofol has ideal anesthetic properties for patients undergoing colonoscopy, a common procedure at outpatient surgery centers.
However, there is a paucity of information regarding patient satisfaction with propofol.
Dr Anantha Padmanabhan and colleagues evaluated patient satisfaction with propofol compared with nonpropofol anesthesia for outpatient colonoscopies.
Safety and complications were secondary end points.
The research team performed a double-blind, randomized, parallel-group controlled clinical trial.
The researchers conducted at a single ambulatory surgery center at an urban teaching community health system.
Patients were scheduled for outpatient colonoscopy.
|26% of propofol procedures were rated “difficult” |
|Diseases of the Colon & Rectum|
Those with high-risk cardiac or pulmonary disease were excluded.
Anesthesia personnel administered either fentanyl/midazolam or propofol for sedation during outpatient colonoscopy.
A single, highly experienced endoscopist performed all colonoscopies.
The team's primary outcomes measured were patient satisfaction and procedure complications.
The research team collected data on the day of endoscopy by the nursing staff of the postanesthesia care unit.
A subinvestigator blinded to the randomization called patients 24 to 72 hours after discharge to obtain data on postprocedure problems and status of resumption of normal activities.
The team observed that fewer patients who received propofol remembered being awake during the procedure, and were more likely to rate the amount of anesthesia received as being “just right”, and state that they were “very satisfied” with their anesthesia.
The researchers noted that 26% of fentanyl procedures were rated “difficult” compared with 4% for propofol, and complications were fewer in the propofol group.
Dr Padmanabhan's team concludes, "Patients prefer propofol over a combination of fentanyl/midazolam as their anesthetic for outpatient colonoscopies."
"From a patient and provider perspective, propofol appears to be superior to fentanyl/midazolam for outpatient colonoscopy."