Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 27 June 2017

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Water exchange method improves adenoma detection rate

The latest issue of the American Journal of Gastroenterology reports that water exchange method significantly improves adenoma detection rate.

News image

Adenoma detection rate is a key colonoscopy quality indicator in Western clinical literature. 

Dr Yanglin Pan and colleagues from California, USA reported that low adenoma detection rate prompted us to assess novel methods to improve performance. 

Western retrospective reports suggested that water exchange could increase adenoma detection rate. 

However, most of these studies used pain score or intubation rate as the primary outcome. 

Overall adenoma detection rate was 18% with water exchange
American Journal of Gastroenterology
The team tested the hypothesis that water exchange significantly increases adenoma detection rate among Chinese colonoscopists, and designed a prospective randomized controlled trial using adenoma detection rate as their primary outcome.

The team performed a prospective, randomized controlled trial at 6 centers in China. 

Screening, surveillance, and diagnostic cases were randomized to be examined by water exchange or traditional air insufflation method. 

The team's primary outcome was adenoma detection rate.

From 2014 to 2015, 3,303 patients were randomized to water exchange and air insufflation. 

The researchers found that baseline characteristics were comparable. 

Overall adenoma detection rate was 18% with water exchange, and 13% with air insufflation. 

The team noted that adenoma detection rate in screening patients using air insufflation was 26% in males, and 16% in females. 

The researchers found that adenoma detection rate in screening patients aged >50 years old was 29% in water exchange, and 23% with air insufflation. 

The increase by water exchange was reproducibly observed in all indication categories, and significant in screening and diagnostic cases. 

The limitation imposed by the unblinded investigators was mitigated by comparable inspection times in cases without polyps, similar adenoma per positive colonoscopy, and reproducible enhancement of adenoma detection rate, and adenoma per colonoscopy by water exchange across all 8 investigators.

Dr Pan's team comments, "This prospective study confirms Western retrospective data that water exchange significantly improves adenoma detection rate among Chinese colonoscopists."

"Water exchange may be superior to air insufflation for screening colonoscopy in China."

"Colonoscopists elsewhere with low adenoma detection rate might consider evaluating water exchange for performance improvement."

Am J Gastroenterol 2017; 112:568–576
21 April 2017

Go to top of page Email this page Email this page to a colleague

 27 June 2017 
Health-related quality of life in eosinophilic esophagitis
 27 June 2017 
Extraintestinal manifestations of IBD
 27 June 2017 
Viral cancers in Barrett’s
 26 June 2017 
Anger in HIV-HCV co-infected patients
 26 June 2017 
Iron and IBD risk
 26 June 2017 
Weight loss for low-income postpartum women
 23 June 2017 
Treatment for KRAS wild-type advanced colorectal cancer
 23 June 2017 
Epidemiology of Hep E
 23 June 2017 
Predictive model for clinical course of Crohn's disease
 22 June 2017 
Vonoprazan-based triple therapy on H. pylori eradication
 22 June 2017 
Adolescent transition in IBD
 22 June 2017 
Patient understanding of biologic therapy in IBD
 21 June 2017 
Statins in chronic Hep C
 21 June 2017 
Racial disparities in colorectal cancer
 21 June 2017 
Hydrolyzed wheat flour improves immunogenicity in celiac disease
 20 June 2017 
Therapies in chronic pancreatitis
 20 June 2017 
Genetic analyses for malignancy detection in biliary strictures
 20 June 2017 
Viral-associated esophagus cancers
 19 June 2017 
Global prevalence of IBS in adults
 19 June 2017 
Clinical improvement in mild acute pancreatitis
 19 June 2017 
Repeat biopsy and celiac disease outcomes 
 16 June 2017 
Exercise-induced GI syndrome—implications for intestinal disease
 16 June 2017 
HCV among reproductive-aged women and children in the USA
 16 June 2017 
Adverse events after outpatient colonoscopy
 15 June 2017 
Pioglitazone for NASH
 15 June 2017 
Treatment of eosinophilic esophagitis
 15 June 2017 
Urinary adverse events after rectal cancer treatment
 14 June 2017 
Genetics of familial colorectal cancer
 14 June 2017 
Abdominal ultrasound in blunt torso trauma
 14 June 2017 
Acute kidney injury in Hep C and sofosbuvir-based regimens
 13 June 2017 
Serrated polyps in the colon and rectum
 13 June 2017 
Colorectal cancer during pregnancy
 13 June 2017 
Biomarker for penetrating Crohn's
 12 June 2017 
Course of primary sclerosing cholangitis
 12 June 2017 
Quality of life in end-stage liver disease
 12 June 2017 
Clinical remission in patients with Crohn's disease
 09 June 2017 
Socioeconomic influences on H. pylori gastritis
 09 June 2017 
Celiac disease in Ireland
 09 June 2017 
Consultants do not follow up on GI tests they recommend
 08 June 2017 
Genetics and the gut microbiota and metabolic syndrome
 08 June 2017 
Antireflux surgery in extraesophageal reflux
 08 June 2017 
Breath testing in gastrointestinal disorders
 07 June 2017 
Multidisciplinary care and liver cancer
 07 June 2017 
Model for excluding NAFLD
 07 June 2017 
Hospital readmission in IBD
 06 June 2017 
Dietary patterns and colorectal cancer risk
 06 June 2017 
Direct-acting antiviral agents for HCV
 06 June 2017 
Medical therapies for stricturing Crohn’s
 05 June 2017 
Hospital-acquired conditions in Crohn’s disease
 05 June 2017 
Celiac disease prevalence in the USA
 05 June 2017 
Depression and IBD
 02 June 2017 
Menopausal hormone therapy and fecal incontinence
 02 June 2017 
Narcotic and corticosteroid prescriptions in IBD
 02 June 2017 
Treating anemia after gastrectomy
 01 June 2017 
Infliximab and cancer in pediatric IBD
 01 June 2017 
Health insurance policies in IBD
 01 June 2017 
Endoscopic quality improvement program for polyp detection
 31 May 2017 
Probiotics and Clostridium difficile infection
 31 May 2017 
Post-procedural adverse events after colonoscopy
 31 May 2017 
Clinical decision-making in severe alcoholic hepatitis

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2017 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us