Dietary fiber is implicated as a risk factor for diverticulitis.
Analyses of dietary patterns may provide information on risk beyond those of individual foods or nutrients.
Dr Lisa Strate and colleagues from Washington, USA examined whether major dietary patterns are associated with risk of incident diverticulitis.
The research team performed a prospective cohort study of 46,295 men who were free of diverticulitis and known diverticulosis in 1986 using data from the Health Professionals Follow-Up Study.
Each study participant completed a detailed medical and dietary questionnaire at baseline.
The researchers sent supplemental questionnaires to men reporting incident diverticulitis on biennial follow-up questionnaires.
The team assessed diet every 4 years using a validated food frequency questionnaire.
Western diets high in red meat, refined grains, and high-fat dairy, and prudent diets high in fruits, vegetables, and whole grains dietary patterns were identified using principal component analysis.
|Men in the highest quintile of Western dietary pattern score had a multivariate hazard ratio of 1.55 for diverticulitis |
Follow-up time accrued from the date of return of the baseline questionnaire in 1986 until a diagnosis of diverticulitis, diverticulosis or diverticular bleeding, death, or 2012.
The team's primary end point was incident diverticulitis.
During 894,468 person years of follow-up, the team identified 1063 incident cases of diverticulitis.
After adjustment for other risk factors, men in the highest quintile of Western dietary pattern score had a multivariate hazard ratio of 1.55 for diverticulitis compared to men in the lowest quintile.
The research team found that high vs low prudent scores were associated with decreased risk of diverticulitis.
The team noted that the association between dietary patterns and diverticulitis was predominantly attributable to intake of fiber and red meat.
Dr Strate's team concludes, "In a prospective cohort study of 46,295 men, a Western dietary pattern was associated with increased risk of diverticulitis, and a prudent pattern was associated with decreased risk."
"These data can guide dietary interventions for the prevention of diverticulitis."