Some studies suggest that Helicobacter pylori infection would be a protective factor for the gastroesophageal reflux.
Dr Ignat and colleagues from Romania explored this fact.
A group of 72 children, admitted in a pediatric gastroenterology regional center in Northeast Romania, diagnosed with gastroesophageal reflux by 24-hour continuous esophageal pH monitoring, underwent upper endoscopy with gastric biopsy to detect the presence of H. pylori by the rapid urease testing and for bacteriological and histologic examination.
The team reported that 26% of children had H. pylori infection, while 74% did not.
The grade of esophagitis was classified according to the Los Angeles classification system.
|26% of children had H. pylori infection|
|Diseases of the Esophagus|
Out of 47 children with esophagitis A, 34% had H. pylori infection, while out of the 25 children with esophagitis B, only 12% had H. pylori infection.
The researchers found that it appears that the presence of the H. pylori determines lower pH-metry scores.
The team observed that the presence of the H. pylori was not an important factor in the gastroesophageal reflux.
On the other hand its relationship with esophagitis appears to be inverse ratio.
Dr Ignat's team concludes, "The fact that the H. pylori presence is statistically greater in the grade A esophagitis could confirm the hypothesis that the bacteria would slow down the development of the esophagitis."