Although the gastrointestinal tract contains intrinsic neural plexuses that allow a significant degree of independent control over gastrointestinal functions, the central nervous system provides extrinsic neural inputs that modulate, regulate, and integrate these functions.
In particular, the vagus nerve provides the parasympathetic innervation to the gastrointestinal tract, coordinating the complex interactions between central and peripheral neural control mechanisms.
|The pathophysiological outcomes of vagus nerve dysfunction resulting in obesity were evaluated|
Dr Guy Boeckxstaens and colleagues from Belgium review the physiological roles of the sensory, and motor vagus in regulation of appetite, mood, and the immune system.
The team also evaluated the pathophysiological outcomes of vagus nerve dysfunction resulting in obesity, mood disorders, and inflammation.
Dr Boeckxstaens' team comments, "The therapeutic potential of vagus nerve modulation to attenuate or reverse these pathophysiological outcomes and restore autonomic homeostasis is also discussed."