As the prevalence of inflammatory bowel disease (IBD) increases in the elderly population, Dr Geoffrey Nguyen and colleagues characterized IBD-related outcomes in this population.
The researchers identified incident IBD cases in Ontario, Canada between 1999 and 2008 and categorized subjects by age at diagnosis as young adults, middle-age adults, and elderly from within population-based health administrative data.
The research team determined the risk of IBD-related surgery, and mortality in those with elderly-onset IBD compared with other age groups.
Of 21,218 persons with IBD, there were 1749 cases of elderly-onset ulcerative colitis (UC), and 725 cases elderly-onset Crohn's disease (CD).
|The leading cause of death in elderly UC was solid malignancies accounting for 23% of deaths|
|Inflammatory Bowel Diseases|
The team found that elderly UC had higher rates of IBD-related surgery than those with young-adult UC, although there was no difference in surgical rates between age groups in CD.
The researchers observed that IBD-specific mortality was higher in elderly-onset CD compared with that in middle-age CD, and young adult CD but was not different by age in UC.
The leading cause of death in elderly UC and CD was solid malignancies accounting for 23% and 26% of deaths, respectively, whereas IBD was third most frequent cause of death accounting for 6% and 9% of deaths, respectively.
Dr Nguyen's team commented, "Elderly-onset patients with UC were more likely to undergo surgery while elderly-onset patients with CD exhibited higher IBD-specific mortality than those with younger-onset disease."
"These findings should prompt more optimized disease management in elderly IBD."