Dr Pontus Karling and colleagues from Sweden compared cumulative ionizing radiation in patients with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) for the years 2001–2011.
The researchers examined how radiation exposure changed over time in patients with newly diagnosed IBD, and factors associated with radiation exposure.
All radiological investigations performed between 2001 and 2011 were retrospectively recorded in patients with Crohn’s disease (CD), ulcerative colitis (UC), and IBS.
The median total cumulative radiation exposure in mSv for CD, UC, IBS, and the proportion of patients who had been exposed for more than 50 mSv during the study period were significantly higher in the patients with CD compared to patients with UC and IBS, respectively.
|Risk factors for radiation exposure included early onset disease|
|Scandanavian Journal of Gastroenterology|
The research team found that patients with UC had significantly higher doses than patients with IBS.
The team identified that risk factors for radiation exposure were female gender, early onset, ileocolonic location, previous surgery, depression, and widespread pain.
In newly diagnosed CD, there was a significant decline in median cumulative radiation dose in mSv during the study period.
Dr Karling's team concluded, "Patients with CD are at greatest risk for high cumulative radiation exposure, but there is a decline in exposure during the late 2000s."
"Non-colectomized patients with UC, and patients with IBS have a relatively low risk of cumulative radiation exposure."