The Multi-Society Task Force, in collaboration with invited experts, developed guidelines to assist health care providers with the appropriate provision of genetic testing and management of patients at risk for and affected with Lynch syndrome.
Dr Giardiello and colleagues from Maryland, USA reported on these guidelines.
The team reported a colorectal cancer risk assessment tool to screen individuals in the office or endoscopy setting.
|The guidelines include a colorectal cancer risk assessment tool to screen individuals in the office|
|American Journal of Gastroenterology|
The guidelines provide a strategy for universal screening for Lynch syndrome by tumor testing of patients diagnosed with colorectal cancer.
The team provided algorithms for genetic evaluation of affected and at-risk family members of pedigrees with Lynch syndrome.
The researchers provided guidelines for screening at-risk and affected persons with Lynch syndrome; and
The team list the guidelines for the management of patients with Lynch syndrome.
Dr Giardiello's team concludes, "We provide a detailed explanation of Lynch syndrome and the methodology utilized to derive these guidelines, as well as an explanation of, and supporting literature for, these guidelines."