According to screening studies, celiac disease is prevalent in Western Europe.
Actual prevalence tends to be much lower.
The width of this actual gap is determined by the balance between disease symptoms and the “case-finding” capabilities of the healthcare system.
Dr Jordy Burger and colleagues from the Netherlands conducted a nationwide study to determine the temporal trends in the incidence in the Netherlands including a focus on demographic aspects.
The researchers performed a nationwide search in the Dutch Pathology Registry (PALGA) to identify all biopsy-proven cases of celiac disease in 5 different years between 1995 and 2010.
Furthermore, demographic profiles and socioeconomic status of patients were studied.
|In men, rates increased from 2.3 to 4.7 per 100,000 in 2010|
|Scandanavian Journal of Gastroenterology|
The overall incidence of celiac disease increased from 2.7 in 1995 to 6.7 per 100,000 inhabitants in 2010.
The research team noted no significant regional differences.
In men, rates increased from 2.3 to 4.7 per 100,000 in 2010.
In women, the increase was from 3.3 to 8.7 per 100,000 in 2010.
The researchers found that a trend toward leveling of incidence was observed from 2008 to 2010.
Patients diagnosed during childhood live in areas with a higher socioeconomic status compared with patients diagnosed at adult age.
Dr Burger's team commented, "The incidence of biopsy-proven celiac disease in the Netherlands increased almost 3-fold between 1995 and 2010."
"In areas with a higher socioeconomic status, relatively more children were diagnosed."